Selection of a Mutant and Optimization of Culture Conditions for the Production of Hyaluronic acid
会议名称:《国际农业工程大会》
会议日期:2004年
学科分类:082903[工学-林产化学加工工程] 08[工学] 0829[工学-林业工程]
摘 要:正 Hyaluronic acid (Hyaluronan, HA for short), is a linear polysaccharide composed of repeating disaccharide units of N-acetyl-glucosamine and D-glucuronic acid. The uronic acid and the amino sugar are linked together by alternating beta-1,4 and beta-1,3 glycosidic bonds (Phrem, 1983). HA exists in many mammalian connective tissues such as joints, vitreous bodies, umbilical cords, cartilages, skins and rooster combs, which contain the polymer at a higher