FXR regulation of collecting duct function
作者单位：AstraZeneca-Shenzhen University Joint Institute of Nephrology
会议名称：《中国生理学会第24届全国会员代表大会暨生理学学术大会》
会议日期：2014年
学科分类：1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学]
摘 要：正Renal collecting ducts play an essential role in water and sodium homeostasis under the regulation of antidiuretic hormone and *** evidence suggests other mechanisms may also be involved in regulating collecting duct *** Farnesoid X receptor（FXR）is a ligand-activated transcription factor belonging to the nuclear receptor *** is mainly expressed in the liver and small intestine,where it plays an important role in bile acid,lipid and glucose