Magnolia Ethanol Extract on Growth of Tumor in Tumor Mice S180
作者单位：College of Pharmacy South-Central University for Nationalities
会议名称：《The 2011 International Conference on Information Technology and Agricultural Engineering(ICITAE 2011)》
会议日期：2011年
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
关 键 词：Magnolia ethanol-extract sarcoma S180 anti-tumor
摘 要：This paper carries on anti-tumor activities research of the ethanol extract of Magnolia officinalis（MEE）. Our results showed that MEE has obvious anti-tumor activities to transplanted tumor model of the mouse S180 sarcoma in vivo. The inhibitory rates of tumor in both MEE 1.0 g/kg and 2.0 g/kg were more than 50 %, however it has not showed a dose-dependent manner. Although it has less damage than cisplatin, MEE can inhibit the immune system by obviously suppressed the spleen index and thymus index. These results indicated the anti-tumor mechanism of MEE might be related to the depressing of immune organs.