Effect of Nanometer preparation of dogwood on the BDNF/TrkB pathway of aging model rats induced by D-galactose
作者单位：Preclinical Medical CollegeJiamusi University
会议名称：《生命的分子机器及其调控网络——2012年全国生物化学与分子生物学学术大会》
会议日期：2012年
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
摘 要：Objective:To explore the relation between the learing and memory capabilities in brain aging model rats and the BDNF-TrkB-ERK signal transduction ***:Forty male SD rats(body weight 350g～400g) were randomly divided into 4 groups,the youth compare group(YCM),the aging model group(AMG),water extract and nanometer particle of dogwood groups(WER and NPR).The AGR rats were induced by injecting D-gal into abdominal cavity daily according to 80mg/kg for 8 *** same doses of dogwood were intragastric administrated to WER and NPR according to 0.57g/kg for 30 *** ability of learning and memory