FPR1 acts as a checkpoint for chemotherapy triggered antitumor response
作者单位：INSERM U1138 Equipe 11 Centre de Recherche des Cordeliers Suzhou Institute of Systems Medicine Chinese Academy of Medical Sciences Gustave Roussy Cancer Campus INSERM U1015
会议名称：《第十届全国免疫学学术大会》
会议日期：2015年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
关 键 词：Chemotherapy FPR1 Immune response Dendritic cells
摘 要：Accumulating evidence suggests that anticancer chemotherapeutic success relies on the elicitation of a durable tumortargeting immune response followingimmunogenictumor cell ***-of-function mutations in immune-related genes have been associated with poor clinical outcome of cancer *** order to further decipher the molecular mechanisms involved in chemotherapy stimulated immune reactions,we tested the presence of 384 preselected single