A New Biflavone from Selaginella pulvinata Maxim

作     者：XU, Kang-Ping XU, Zhi DENG, Yin-Hua LI, Fu-Shuang ZHOU, Ying-Jun HU, Gao-Yun TAN, Gui-Shan ( Department of Medicinal Chemistry , School of Pharmaceutical Sciences , Central South University , Changsha 410078 ) 

会议名称：《第三届全国有机化学学术会议》

会议日期：2004年

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

摘      要：正 Selaginella pulvinata Maxim. distributes all over the country of China and is used for the treatment for haemor-rhage. We studied on the chemical constituents of S. pulvinata in order to find the active compounds. Dried stems and leaves of S. pulvinata （6.5 kg） were extracted with 70% ethanol twice. The extract was evaporated un-der vacuum and than suspended in water, extracted with petroleum and EtOAc sequentially. The EtOAc extract was chromatographed on silica gel, eluted with CHCI3-MeOH. As a result, a novel biflavone, named pulvinatabiflavone, was obtained from fractions 75-78. Its structure was determined on the basis of spectroscopic analysis as 5,5″, 4 -