Humoral and cellular immune responses induced by SARS or SARS-like coronavirus 3a DNA vaccine in mice

作     者：Baojing Lu,Ling Tao,Ting Wang,Zhenhua Zheng,Bao Li,Ze Chen,Yi Huang,Qinxue Hu and Hanzhong Wang (State Key Laboratory of Virology,Wuhan Institute of Virology,Chinese Academy of science, Wnhan 430071,PR China 2 Graduate University of Chinese Academy of Sciences,Beijing 100049) 

会议名称：《中国微生物学会《第二届全国农业微生物研究及产业化研讨会》和《第十一届全国杀虫微生物学术研讨会》暨《湖北省暨武汉市微生物学会和内蒙古微生物学会2008年会》》

会议日期：2008年

学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学] 

摘      要：3a gene is a newly identified group-specific open-reading frame(ORF)found in both SARS-CoV and SARS-Like-CoV(SL-CoV).In this study,the immunogenicity of human SARS-CoV and bat SL-CoV 3a DNA vaccines have been *** date showed that specific humoral and cellular immune responses were induced by