Receptor-Ligand Pharmacophore Generation Protocol in Discovery Studio
作者单位：Accelrys Inc.10188 Telesis CourtSuite 100San DiegoCA 92121USA
会议名称：《2011年全国药物化学学术会议——药物的源头创新》
会议日期：2011年
学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
摘 要：正Pharmacophore modeling is an important step in early stage of drug *** pharmacophore tools in Discovery Studio platform have been widely used by pharmaceutical *** increasing number of high-quality x-ray structures of receptor-ligand complexes provides a new way for pharmacophore generation directly from the 3D structures of protein