The prostate epithelial androgen receptor functions as a suppressor for prostate cancer metastasis
作者单位：George Whipple Laboratory for Cancer ResearchDepartments of PathologyUrologyand the James P.Wilmot Cancer CenterUniversity of RochesterRochesterNew York 14620USA.
会议名称：《2007年浙江省男科学学术年会》
会议日期：2007年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：Targeting androgens via androgen deprivation therapy(ADT)to suppress androgens/androgen receptor(AR)functions remains the standard treatment for prostate cancer. However, most tumors eventually recur in spite of ADT. Here we demonstrate that the prostate epithelial AR may function as a suppressor for prostate cancer metastasis. Results from orthotopically co-inoculated stromal WPMY1 cells