Rapamycin attenuates the development of chronic hypoxia-induced pulmonary hypertension in mice

作     者：Wang Wang,Jie Liu,Ran Miao,Jing Li,Ji-Feng Li,Xiao-Min Yu, Li-Juan Guo,Yuan Lin,Chen Wang,Jun Wang 1 epartment of Physiology,Capital Medical University 2 eijing Key Lab of Respiratory and Pulmonary Circulation Disorders,Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital,Capital Medical University 

会议名称：《中华医学会呼吸病学年会——2011（第十二次全国呼吸病学学术会议）》

会议日期：2011年

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学] 

摘      要：Background Pulmonary hypertension(PH) is characterized by a progressive increase in pulmonary vascular resistance,structural remodeling of the pulmonary vasculature,finally,right ventricular failure and *** trigger of PH is hypoxia which chronically leads to vascular proliferation and *** proliferation of smooth muscle cells is now recognized to play a