SARS Structural Genomics: The First Crystal Structures of SARS Virus Main Protease Mpro and Its Complex with an Inhibitor
会议名称：《第七届全国酶学学术讨论会》
会议日期：2004年
学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
摘 要：A newly identified coronavirus,SARS-CoV,is the etiological agent responsiblefor the outbreak of severe acute respiratory syndrome(SAGS).We have initiated aStructural Genomics study of all structural,non-structural and hypothetical proteins inthe SARS *** main protease(Mpro),which is a 34.6 kDa protease(also