Evolution of the design of Venturi devices for the delivery of dry particles to skin or mucosal tissue
作者单位:Department of Engineering ScienceUniversity of OxfordOxford OX2 6PEUnited Kingdom
会议名称:《The 24th International Symposium on Shock Waves》
会议日期:2004年
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 10[医学]
摘 要:The behaviour of bursting membrane devices, used to accelerate powder particles to velocities high enough to penetrate the skin, has been extensively studied at Oxford University. Over-expansion of a supersonic jet leads to flow separation, and powder concentrates in this separated jet[1,2]. Correctly expanded shock tube devices, which produce uniform gas velocities[4], require the powder to be delivered over a narrow time window (of order 0.2 ms) to be accelerated to maximum velocity. This paper reviews the evolution of devices designed to use the Venturi effect to entrain particles into a quasi-steady gas flow.