Evolution of the design of Venturi devices for the delivery of dry particles to skin or mucosal tissue
作者单位：Department of Engineering ScienceUniversity of OxfordOxford OX2 6PEUnited Kingdom
会议名称：《The 24th International Symposium on Shock Waves》
会议日期：2004年
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 10[医学]
摘 要：The behaviour of bursting membrane devices, used to accelerate powder particles to velocities high enough to penetrate the skin, has been extensively studied at Oxford University. Over-expansion of a supersonic jet leads to flow separation, and powder concentrates in this separated jet[1,2]. Correctly expanded shock tube devices, which produce uniform gas velocities[4], require the powder to be delivered over a narrow time window (of order 0.2 ms) to be accelerated to maximum velocity. This paper reviews the evolution of devices designed to use the Venturi effect to entrain particles into a quasi-steady gas flow.