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文献详情 >Liquiritigenin inhibits amyloi... 收藏
Liquiritigenin inhibits amyloid β-peptide-induced neurotoxi...

Liquiritigenin inhibits amyloid β-peptide-induced neurotoxicity,the secretion of amyloid β-peptide as well as fibril formation in vitro

作     者:Ruiting Liu~(1,2) Guangxing Bian~1 Libo Zou~2 Qiujun Lu~(1*) 1.Institute of Radiation Medicine,Academy of Military Medical Science,Beijing,100850,China 2.School of Life Science and Biological Pharmacy,Shenyang Pharmaceutical University,China 

会议名称:《2008年全国抗衰老与老年痴呆学术会议》

会议日期:2008年

学科分类:1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

关 键 词:liquiritegenin selective ERβagonist neuroprotective Aβsecretion fibil formation 

摘      要:Background and Purpose:Amyloidβ-peptide(Aβ)is a pivotal pathological factor in Alzheimer’s disease(AD).Estrogen is beneficial to patients with AD but its proliferation and oncogenic effects on non-neuronal cells has dampened the enthusiasm for the use of estrogen

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