Bioinformatics and interactions of heavy metals and peptides based on bacterial display technology
作者单位：Laboratory of Molecular Evolution and Applied BiologySchool of Life Science and EngineeringSouthwest Jiaotong University
会议名称：《中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议》
会议日期：2010年
学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 07[理学] 071005[理学-微生物学] 10[医学]
关 键 词：bioinformatics heavy metals display interaction metal binding peptide.
摘 要：Molecular interactions have already been the interest of life science research,the study of the interactions between heavy metal ions and metal binding peptides(protein) has been an important and active area of bioinorganic chemistry,as well the especially difficult area of molecular interaction. In this study,homology blast,sequence alignment and construction of molecular cladogram of 121 heavy metal binding peptides from various origins with different heavy metal specificities were analyzed by Clustal X for multiple sequence alignment and other bioinformatics methods,then on the basis of our lab’s previous work,oligonucleotides of