Genomic organization of human long non-coding ACAT1C7 gene and its promoter activity
作者单位：State Key Laboratory of Molecular BiologyInstitute of Biochemistry and Cell BiologyShanghai Institutes for Biological SciencesChinese Academy of Sciences Department of BiochemistryDartmouth Medical School
会议名称：《中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议》
会议日期：2010年
学科分类：1001[医学-基础医学(可授医学、理学学位)] 10[医学]
摘 要：Acyl-coenzyme A:cholesterol acyltransferase(ACAT) is a key enzyme playing important roles in cholesterol *** catalyzes the formation of cholesteryl ester from cholesterol and long-chain fatty acyl-coenzyme A in various cell *** mammals,two ACAT genes encoding ACAT1 and ACAT2 have been *** sequence of human ACAT1 mRNA is produced from two different chromosomes 1 and 7 with individual promoters P1 and P7,named ACAT1 gene and ACAT1C7 gene respectively. Our previous studies have revealed the promoter activity