Eantioselective Synthesis of Bicyclic δ-Lactones via N-Heterocyclic Carbene Catalysis
作者单位：Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry Chinese Academy of Sciences
会议名称：《中国化学会第九届全国有机化学学术会议》
会议日期：2015年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
摘 要：正In the past decade,N-heterocyclic carbenes（NHCs）have been demonstrated as powerful catalysts for various reactions.[1]Firstly explored by Bode et al.[2]and Glorius et al.[3],the NHC-catalyzed reactions of enals are extremely ***,we report the NHC-catalyzed cascade reaction of enals with malonates to generate bicyclicδ-enollactones[4]in high yields with