An Artificial Zinc Activated Ion Channel Based on Zinc Fingers Immobilized Single Polymeric Nanochannel

作     者：Ye Tian,Fuqiang Nie~*,Lei Jiang~* (Center of Molecular Sciences,Institute of Chemistry,Chinese Academy of Sciences,North First Street,ZhongGuanCun,Beijing,100190) 

会议名称：《全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会》

会议日期：2010年

学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 

摘      要：In this work,we reported an artificial zinc activated ion channel by immobilizing zinc finger peptides into a single polymeric *** on the conformational changes of zinc fingers,the artificial ion channel we produced here shows a zinc activated *** is,there are few ions pass through the channel in the absence of zinc,whereas after zinc binding,zinc fingers fold to finger-like conformations,which result in the in-