Contribution of PHD2 to therapeutic angiogenesis through HIF-dependent and HIF-independent manner
作者单位：The "111 Project"Laboratory of Biomechanics and Molecular MedicineCollege of BioengineeringUniversity of Chongqing
会议名称：《第十届全国生物力学学术会议暨第十二届全国生物流变学学术会议》
会议日期：2012年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：supported by the“111 Project”of China(No.B06023,L.Yang) the recruitment fund from Chongqing University(No. 0221005303137,S.Wu)
摘 要：Ischemia occurs when blood vessels in tissues are blocked,and affects hundreds of millions of people *** vascular diseases include peripheral arterial disease,inferior limb ischemia,ischemic heart, *** strategy so far aims to improve neovascularization in ischemic tissues by delivering angiogenic factor proteins or DNA vectors encoding *** make the cells well adaptive to low oxygen tension(hypoxia) the cellular hypoxic response includes various alterations in gene *** them Hypoxia-in-