Determination of the human antibody response to the neutralization epitopes of glycoproteins E1E2 and its broad cross-genotype neutralizing activity in hepatitis C virus infection individuals
作者单位:Peking University People’s Hospital Peking University Hepatology Institute Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases
会议名称:《2012中国消化系疾病学术大会》
会议日期:2012年
学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
摘 要:Objective To determinate the prevalence of 5 neutralization epitope-binding antibodies and their cross-genotype neutralizing activity in Hepatitis C Virus Infection Individuals. Methods Antibodies response to each epitope peptide in serum samples from HCV chronic infection and spontaneous clearance individuals were detected by the indirect *** HCV-pseudotyped particles