Dynamic nucleosome positioning in human CD4+ T cell
作者单位:东南大学生物电子学国家重点实验室
会议名称:《第四届全国生物信息学与系统生物学学术大会》
会议日期:2010年
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
关 键 词:dynamic regulation nucleosomes gene expression
摘 要:In this study,dynamic nucleosome positioning in human CD4+ T cell was *** explained that nucleosome level in the region of~200-bp upstream of TSS behaves like a lighthouse that determines whether a gene can express. And nucleosome dynamic change of promoters is different from other *** considered that there is a different pattern of nucleosome dynamic regulation between promoters and other important regions.