Phytochemical Guttiferone K Triggers Apoptosis Through Inducing Endoplasmic Reticulum Stress Aggravation in Colorectal Cancer Cells
作者单位：School of Biomedical SciencesThe Chinese University of Hong Kong School of PharmacyThe Chinese University of Hong Kong Shanghai University of Traditional Chinese Medicine
会议名称：《第十四届全国中药和天然药物学术研讨会》
会议日期：2014年
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
摘 要：正Guttiferone K（GutK）is a polycyclic polyprenylated acylphloroglucinol（PPAP）isolated from Garcinia *** group had previously confirmed that GutK can trigger apoptosis in colorectal cancer cells,however,the mechanism underlying GutK-induced apoptosis is *** present study demonstrated that GutK elicited endoplasmic reticulum（ER）stress in a variety