An Efficient Protocol for the Reduction of Azidonucleosides Catalyzed by Raney Nickel

作     者：QU, Gui-Rong LIU, Qi-Bin (Key Laboratory of Environmental Science and Technology of High Education of Henan Province, College of Chemical and Environmental Science , Henan Normal University, Xinxiang 453002) 

会议名称：《第三届全国有机化学学术会议》

会议日期：2004年

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

基　　金：Project supported by the National Natural Science Foundation of China(No.29972010) 

摘      要：正 Aminonucleosides are very important intermediates in the synthesis of anti-sense and anti-gene drugs, nucleic acid analogues, diagnostic and analytical agents, antitumor and antiviral compounds. In the presence of Raney nickel, the reduction of various azidonucleosides to the corresponding aminonucleosides is in good yields （Table 1, Scheme 1）.