Relationship between Dietary Glycemic Load and Levels of Blood Glucose and Lipid in Patients with Newly-diagnosed Type 2 Diabetes
作者单位：Department of Clinical Nutrition Sun Yatsen memorial hospital Sun Yatsen University
会议名称：《第十七届中国科协年会——分12 新时代下大营养观专题论...》
会议日期：2015年
基 金：financial support from Science and Technology Planning Project of Guangdong Province(2011B031800018)
关 键 词：type 2 diabetes mellitus glycemic load blood glucose blood lipid
摘 要：To observe the dietary glycemic load(GL) in patients with newly-diagnosed type 2 diabetes mellitus(T2DM), and discuss the relationship between dietary GL and blood glucose and lipid, 201 patients with newly-diagnosed T2 DM and 126 people with normal blood glucose above 40 years old in communities of Guangzhou were enrolled. Carbohydrate(CHO) intake and GL were assessed based on 3-d dietary records. With GL as the dependent variable, correlation analysis and multiple regression were used to analyze the relationship between dietary GL and concentrations of blood glucose and lipid. The results showed that dietary GL in patients with newly-diagnosed T2 DM was significantly higher than control group((169.61±44.83) vs(157.50±38.47), P0.05). Correlation analysis showed that dietary GL was positively correlated with BMI and Hb A1 c in patients with T2DM(r=0.187, P0.01 and r=0.154, P0.05, respectively), while negatively correlated with HDL-C in both control group and diabetes group(r=-0.197, P0.05 and r=-0.207, P0.01, respectively). Adjusted for age and sex by multiple regression, the result was the same. It is concluded that high-GL diet may be associated with the occurrence of T2 DM, and is closely related to glucose control and blood lipid metabolism. It is necessary for both patients with diabetes and healthy people to control dietary GL.