Systematic characterization of ISGs that can inhibit influenza virus replication
作者单位:中国医学科学院基础医学研究所
会议名称:《第九届全国免疫学学术大会》
会议日期:2014年
学科分类:1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学]
摘 要:Background:Type I interferons(IFN-alpha/beta)play an essential roles during the innate immune response to viral *** are recognized by IFN-alpha/beta receptor firstly,then JAK/STAT-dependent and STAT independent pathways are *** last,several interferon stimulated genes(ISG)are expressed as direct antiviral effectors to fight against