Progress and challenges of experimental integrative medicine in abroad
会议名称：《第十一次中国中西医结合实验医学学术研讨会》
会议日期：2013年
学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学]
摘 要：Experimental studies on integrative medicine has made progress during the past 15 years, since as many as 42%of patients in the *** complementary alternative medicine(CAM) to fulfill their needs in lieu of or as an adjunct to conventional ***,several well-designed clinical trial studies reported negative results of acupuncture on treatment of hypertension and *** United Kingdom decided to halt the sale of traditional herbal medicinal products due to toxins,pesticides,and failure to meet standards of safety, quality,and *** of this let us to think the research direction of experimental integrative medicine and how to study traditional Chinese medicine(TCM).Based on TCM meridian theory,a biocapture device has been develop and taped to the skin surface along the meridian lines over the Pericardium Meridian(PC) and the Bladder Meridian(BL) and filled with a collecting solution for 20 *** of total nitrate and nitrite(NOx-), cGMP and nitrotyrosine,a stable end-product of peroxynitrite(ONOO),in the samples were quantified using chemiluminescence and ***-cGMP and nitrotyrosine concentrations were assayed over acupoints,meridian line without acupoint,and non-meridian control following Device(RespeRate)-guided slow breathing exercises in healthy volunteers and hypertensive patients. Results show that NOx-and cGMP concentrations are consistently higher over PC acupoints compared to non-meridian control in healthy *** levels are decreased and levels of nitrotyrosine over acupoints are as much as 6 fold higher in hypertensive subjects compared to normotensive healthy *** breathing exercises(20 min twice daily) increased cGMP levels over acupoints in both normotensive and hypertensive *** concentrations and arterial blood pressure are significantly reduced following a 7-day period of the slow breathing exercises in hypertensive *** conclude that ONOO/NO-cGMP can be simultaneously qua