Neuroprotective effect of insulin-like growth factor-1:effects on tyrosine kinase receptor(Trk) expression in dorsal root ganglion neurons with glutamate-induced excitotoxicity in vitro
作者单位:Department of AnatomyShandong University School of Medicine Department of OrthopaedicsShandong University Qilu hospital Department of Computer Tomography and Magnetic Resonance ImagingWeifang Medical College Affiliated Yidu Central Hospital Shandong Provincial Key Laboratory of Mental DisordersShandong University School of Medicine Department of RheumatologyShandong University Qilu Hospital
会议名称:《华东六省一市第22届解剖与组织胚胎学学术年会暨山东解剖...》
会议日期:2013年
学科分类:1001[医学-基础医学(可授医学、理学学位)] 100104[医学-病理学与病理生理学] 10[医学]
摘 要:正Insulin-like growth factor-1(IGF-I) may play an important role in regulating the expression of distinct tyrosine kinase receptor(Trk) in primary sensory dorsal root ganglion(DRG) ***(Glu) is the main excitatory neurotransmitter and induces neuronal excitotoxicity for primary sensory *** is not known whether IGF-1 influences expression of TrkA,TrkB,and