Overexpression of thioredoxin in transgenic mice reduces neuronal degeneration after mild focal ischemia
作者单位:Department of NeurosurgeryGraduate School of MedicineKyoto University
会议名称:《2007浙江省神经外科学学术年会》
会议日期:2007年
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
摘 要:Thioredoxin(Trx)is a small,multifunctional protein with a redox-active site and multiple biological functions including attenuation of reactive oxygen *** damage is one of the most damaging stress in the pathological process of *** induced a 30-min transient middle cerebral artery occlusion(MCAO)model in Trx overexpressing mice(Tg)and control C57BL/6 mice(WT)