Simultaneous NF-κB inhibition and E-cadherin uPregulation mediate mutually synergistic anticancer activity of celastrol and SAHA in vitro and in vivo
作者单位：Institute of Pharmacology and Toxicology College of Pharmaceutical SciencesZhejiang University
会议名称：《第八届中国肿瘤学术大会暨第十三届海峡两岸肿瘤学术会议》
会议日期：2014年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要：正Objective The anticancer activity of the HDAC inhibitor SAHA was imPeded by the activation of *** hyPothesized that celastrol,an NF-kaPPaB inhibitor,combined with SAHA might exert synergistic effect against cancer *** 1)The anticancer efficacy