Defects in the Ryanodine Receptor Channel Associated with Cardiac Arrhythmias
作者单位：Dept.of Molecular Physiology and Biophysics and MedicineBaylor College of MedicineHoustonTX
会议名称：《中国药理学会药学监护专业委员会第一届第三次学术大会》
会议日期：2007年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要：Cardiac arrhythmia is an important cause of death in patients with heart failure (HF)and inherited arrhythmia syndromes,such as catecholaminergic polymorphic ventricular tachycardia(CPVT).Recent studies indicate that alterations in intracellular calcium(Ca2+)release channels known as ryanodine receptors(RyR2)