Recent Progress in Triazole Derivatives as Medicinal Agents

作     者：Yan Wang,Xin-Mei Peng,Bo Zhang,Hui-Zhen Zhang,Juan-Juan Chang,and Cheng-He Zhou~* School of Chemistry and Chemical Engineering,Southwest University,Chongqing,400715,China 

会议名称：《2011年全国药物化学学术会议——药物的源头创新》

会议日期：2011年

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the Natural Science Foundation of China(21172181) Chongqing (CSCT2007BB5369) Southwest University(SWUB2006018 and XSGX0602) the Fundamental Research Funds for the Central Universities(XDJK2011D007) 

摘      要：正The five-member aromatic triazole ring could easily interact with a variety of enzymes and receptors via diverse non-covalent bonds such as coordination,hydrogen bonds,ion-dipole, cation-π,π-πstacking,hydrophobic effect,van der Waals force and so on,and therefore display versatile biological *** specially structural characteristic also makes triazole