TIMP-3 expression associates with malignant behaviors and predicts favorable survival in HCC
作者单位:Department of Hematology and OncologyJiangsu Provincial Hospital Department of PathologyJiangsu Provincial Hospital Department of Clinical LaboratoryJiangsu Provincial Hospital
会议名称:《第十四届全国老年医学进展学术会议暨江苏省中西医结合学会老年分会学术年会》
会议日期:2014年
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
摘 要:The tissue inhibitors of metalloproteinases(TIMPs)are the proteins that specifically inhibit the proteolytic activity of matrix metalloproteinases(MMPs)and TIMP-3has been identified as a unique tumor suppressor which is the only member of the TIMPs that could tightly bind to the extracellular matrix and is demonstrated to inhibit