Aspirin Induces Apoptosis in Mesenchymal Stem Cells Requring Wnt/β-catenin Pathway
作者单位：Research Center for Cardiovascular Regenerative Medicinethe Ministry of Health of ChinaCardiovascular Institute and Fu Wai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina
会议名称：《2008年全国生物化学与分子生物学学术大会》
会议日期：2008年
学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
摘 要：Mesenchymal stem cells(MSCs)have been reported to improve heart function when injected into the myocardium after an *** have previously observed that aspirin,a standard medication for the primary and secondary prevention of cardiovascular diseases,inhibits MSCs proliferation and here we demonstrate that aspirin induces MSCs *** induced apoptotic morphological changes,cytochrome c release from