CENTRAL VENOUS CATHETERISATION DURING NEUTROPENIA OR LEUKOCYTOSIS DO NOT INCREASE THE INFECTION RATE OF CENTRAL LINES IN CHILDREN WITH MALIGNANCY
作者单位：Division of Paediatric SuretyDepartment of SurgeryThe University of Hong KongQueen Mary HospitalHong Kong. Division of Paediatric SurgeryDepartment of SurgeryThe University of Hong KongQueen Mary HospitalHong Kong
会议名称：《2000全国肿瘤学术大会》
会议日期：2000年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
关 键 词：Central venous catheter White cell count Neutropenia
摘 要：A total of 24 catheterizations in 16 children with malignancy, admitted into Queen Mary Hospital,Hong Kong,between April 1987 and July 1993,were studied *** cell counts(WCC),taken within the 24 hour period prior to catheterisation,were *** were cate- gorized into four groups:1)neutropenia(WCC? 1.0×10/L),2)subnor- mal(WCC between 1.0 and 3.5×10/L), 3)normal(WCC between 3.5 and 11.0×10/L) and 4)leukocytosis(WCC?11.0×10/L).The mean age of the patients was 4.4 *** total duration of catheterisation was 4801 *** central venous line infection rates for groups 1,2,3 and 4 were 5.3,1.3,1.6 and 2.4 infection per 1000 days of catheter use respec- *** these four groups,we found no difference in the infection rates of central venous catheters(p=0.64,χ-square).When the groups 1, 2 and 4 were compared to group 3(normal),no difference was detected either (p=0.34,1.00 and 0.65 respectively,Fisher’s exact test).We conclude that central venous catheterization in children with malignancy under antibiotic cover during neutropenia or leukocytosis is not contraindicated.