Nematode infection improve metabolic homeostasis via M2-polarization of adipose tissue macrophage(ATM)
作者单位:Zhongshan School of MedicineSun Yat-sen University 中山大学中山医学院 Department of Medicine & MBRCUniversity of Maryland School of MedicineBaltimoreMDUSA
会议名称:《生命的分子机器及其调控网络——2012年全国生物化学与...》
会议日期:2012年
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要:Background:Obesity is associated with chronic low grade inflammation characterized by an increased level of proinflammatory cytokines/mediators that are implicated in disrupted metabolic *** nematode infection induces a polarized Th2 cytokine re-sponse and has been shown to counteract ***:to investigate the effects of enteric nematode infection against obesity and the associated metabolic syndrome and to explore the underlying molecular *** and Methods: