Effect of propofol on inflammatory cytokines in rats following cerebral ischemia-reperfusion

作     者：Xiu-zhen Lei Department of Anaesthesiology, First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310003,china 

会议名称：《2006年浙江省麻醉学学术年会》

会议日期：2006年

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

关 键 词：ischemia/reperfusion injury tumor necrosis factor-alpha (TNF-α) interleukin-1β (IL-1β) interleukin-6 (IL-6) interleukin-8 (IL-8) propofol rat 

摘      要：Objective To explore changes of tumor necrosis factor-alpha (TNF-α). interleukin-1β (IL-1β), interleukin-6 (IL-6 ),interleukin-8 (IL-8), malondialdehyde (MDA), and superoxide dismutase (SOD) in plasma and the effect of propofol on these cytokines in rats following cerebral ischemia-reperfusion injury. Methods Focal cerebral ischemia model was induced with occluding the middle cerebral artery