PcrV Antibody Prophylaxis in Combination with Antibiotic Therapy Reduces Lung Injury and Improves Survival in Pseudomonas aeruginosa Infected Mice
作者单位：美国加州大学旧金山分校麻醉科
会议名称：《中华医学会呼吸病学年会——2011（第十二次全国呼吸病学学术会议）》
会议日期：2011年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要：The typeⅢsecretion system(TTSS) of Pseudomonas aeruginosa,associated with acute infection and ventilator-associated pneumonia(VAP),facilitates direct injection of cytotoxins into host cell ***,located at the tip of the needle-like injectosome,is an essential component of this virulence ***166,a murine monoclonal antibody against PcrV has demonstrated efficacy