The association between the single nucleotide polymorphisms in the three loci in PPAR-γ gene and susceptibility to non-alcoholic fatty liver disease
作者单位：Guangzhou First Peoples Hospital
会议名称：《中华医学会第十六次全国病毒性肝炎及肝病学术会议》
会议日期：2013年
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要：Aims We have previously shown that single nucleotide polymorphisms(SNPs) at C161T in the peroxisome proliferator-activated receptors-γ(PPAR-γ) gene were associated with the susceptibility to non-alcoholic fatty liver disease(NAFLD)(Liver Int.2008,28;385).In this study,we further investigated the effect of the SNPs at three other loci in PPAR-γgene i.e.C-681G,C-689T and Prol2Ala on the susceptibility to