New Advances in the Treatment of Acne and Rosacea
作者单位：University of Pennsylvania School of Mediane
会议名称：《中华医学会第14次全国皮肤性病学术年会》
会议日期：2008年
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
摘 要：This talk will review several new advances in the treatment of acne and rosacea. Dose response studies with minocycline demonstrate 1 mg/kg as the ideal dose in contrast to the commonly used 2mg/kg. Absorption stud- ies with minocycline reveal a wide range of absorption which have implications for efficacy and side effect pro- files. Recent studies with a topical combination of tretinoin and clindamycin show that this formulation of treti- noin is not associated with flaring of inflammatory lesions in the early phase of treatment contrary to the widely held belief that topical retinoids induce a flare of inflammatory lesions. A formulation of 5% dapsone has been approved by the F. D.A. for the treatment of inflammatory ache. A recent study in 100 G-6-P-D deficient