Identification of Complex Constituents in Herba Sarcandrae Using High Speed Accurate Mass Technology
作者单位：Key Laboratory of Modern Preparation of TCM Jiangxi University of Traditional Chinese Medicine
会议名称：《BCEIA2013分析仪器应用技术报告会》
会议日期：2013年
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 100602[医学-中西医结合临床] 10[医学]
摘 要：It is well accepted, that traditional Chinese medicines(TCM) achieve efficacy based on synergy of multi-components, even some lower level components may play an important role in mechanism of actions. Therefore, it is crucial to develop an effective, comprehensive and reliable analytical method for identification of active constituents of TCM. This poster we described: Targeted and non-targeted workflows for identifying complex components of Herba Sarcandrae using TripleTOF 5600+ system. Ninety-seven compounds including 53 previously reported compounds and 44 newly identified / tentatively characterized compounds represent the largest dataset of compounds identified in Herba Sarcandrae plant *** combination of high scan rate speed, highly sensitive accurate mass, and rapid chromatographic separations, and powerful software based workflows enabled the identification of many novel compounds. Accurate mass technology has been proved to be a powerful tool in structure characterization