The development and use of (Q)SAR models for the evaluation of Genotoxic Impurities
作者单位：Lhasa LtdLeedsLS2 9HDUnited Kingdom
会议名称：《中国毒理学会第三届中青年学者科技论坛暨2011年全国前列腺药理毒理学研讨会》
会议日期：2011年
学科分类：100405[医学-卫生毒理学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学]
摘 要：Purpose of Study The advent of guidelines on genotoxic impurities(GTIs) from,both the EMEA and the FDA has led to the routine use of(Quantitative) Structure Activity Relationships[(Q)SAR]models in the evaluation of potential GTIs within the pharma industry.(Q)SAR models rely on data