Tp receptor activation impairs endothelial nitric oxide-dependent vasorelaxation to isoprenaline:role of rho kinase in endothelium
作者单位：Department of PhysiologyChinese University of Hong KongChina
会议名称：《浙江省生理科学会2008年学术年会》
会议日期：2008年
学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
基 金：supported by Research Grants Council of Hong Kong SAR(CUHK 4366/03M and 4362/04M) CUHK Focused Investment Scheme,and by a grant from Li Ka Shing Institute of Health Sciences.FPL is a Postdoctoral Fellow supported by these grants CQL was supported by the National Natural Science Foundation of China(No.3047627)
关 键 词：Endothelium Isoprenaline Nitric oxide TP receptor
摘 要：Activation of TP receptors causes potent vasoconstriction,which contributes to increased vascular tone and blood *** present study was designed to examine the hypothesis that stimulation of TP receptor impairs endothelium-dependent vasorelaxation to isoprenaline via Rho kinase