Early lesions in small intestinal Crohn's disease: An endoscopic and confocal endomicroscopic appraisal
作者单位：Fudan University Children’s Hospital Shanghai and Precious Blood Hospital
会议名称：《第十届全国儿童消化系统疾病学术会议》
会议日期：2014年
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
摘 要：The pathogenesis of Crohn’s disease is complex and involves various factors that interplay in the initial and persistent damage to the intestinal tissue which begins at the mucosal layer with eventual spread to the other layers of the intestine. It probably involves defects in immunoregulation and maintenance of the mucosal barrier. But exactly how such functional changes are translated to morphological deformities is unknown and the earliest morphological changes, believed to be an aphthoid ulcer, has not been well characterized, especially in the small intestine.