Epithelial-mesenchymal transition is required for acquisition of cisplatin resistance and increases metastatic potential in nasopharyngeal carcinoma cells
作者单位：Faculty of pharmacyBengbu Medical College School of Medicine and Public HealthFaculty of HealthUniversity of Newcastle
会议名称：《2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议》
会议日期：2013年
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
关 键 词：Nasopharyngeal carcinoma cisplatin chemoresistance EMT invasion migration
摘 要：Background Radiotherapy and adjuvant cisplatin chemotherapy are the mainstream approaches in the treatment of nasopharyngeal carcinoma(NPC).However,chemotherapy resistance in the course of treatment has recently become more common,resulting in the failure in NPC *** aim of this study was to assess cisplatin-resistant NPC cells for cellular