A law of mutation:Small insertions and deletions decay exponentially to their sizes

作     者：Jia Zhang~1 Li Xiao~2 Lideng Liu~2 Hanlin Gao~(2,3) Kai Li~(2,3) (1.Functional Genomics Institute of Norvatis,San Diego,CA92121,USA 2.Clinical Molecular Diagnostic Center,The second affiliated hospital.Suzhou University,Suzhou,China 3.Human Genetics,City of Hope National Cancer Center,Duarte,CA 91010,USA) 

会议名称：《遗传学进步与人口健康高峰论坛》

会议日期：2007年

学科分类：0710[理学-生物学] 07[理学] 071007[理学-遗传学] 

摘      要：Incidences of small indels decay rapidly according to the size of inserted or deleted *** analysis of small indels revealed that the decay of small insertions/deletions is proportional with the square of the number of base pairs inserted or deleted,which is described as M=M×*** type of decay has been observed in randomly occurred genetic alterations including inherited mutations,somatic mutations,and small gaps from sequence alignment within or between