Chromosome location, molecular characterization, polymorphisms and expression of G protein-coupled receptor 54 (GPR54) as a candidate gene for puberty in pigs

作     者：S.-J. LI, J. REN. L.-S. HUANG Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nangchang, 330045, P. R. China 

会议名称：《湖北省遗传学会、江西省遗传学会2006年学术年会暨学术讨论会》

会议日期：2006年

学科分类：0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

关 键 词：GPR54 Chromosome location as a candidate gene for puberty in pigs molecular characterization polymorphisms and expression of G protein-coupled receptor 54 

摘      要：G-protein coupled receptor (GPR54) is a member of the rhodopsin family and plays a key role in activating the pulsatile release of hypothalamic gonadotropin-releasing hormone, which is crucial for puberty onset. The aim of this study was to characterize GPR54 and provide a starting point for evaluating the association of the variants in this gene with puberty in pigs. GPR54 was assigned to SSC2q21-24 by radiation hybrid mapping, and the most significantly linked marker is SW395 at a