Inhibitory effect of Sodium Tanshinone IIA Sulfonate on pulmonary arterial smooth muscle canonical transient receptor potential expression in pulmonary hypertensive rats
作者单位:Guangzhou Institute of Respiratory DiseaseState Key Laboratory of Respiratory DiseasesThe 1st Affiliated Hospital of Guangzhou Medical UniversityChina Division of Pulmonary & Critical Care MedicineJohns Hopkins Medical InstitutionsBaltimoreMD 21224
会议名称:《中华医学会呼吸病学年会——2013(第十四次全国呼吸病学学术会议)》
会议日期:2013年
学科分类:1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
摘 要:Rationale:Danshen,the dried root of Salvia miltiorrhiza, is famous for its reliable effects in treating various diseases# Sodium Tanshinone IIA sulfonate(STS),a water-soluble derivative of tanshinone IIA,one of the most abundant constituents of Danshen,was recently reported to be effective in attenuating the characteristic pulmonary vascular changes associated with chronically hypoxic pulmonary hypertension(CHPH).However,the underlying detailed mechanisms remain poorly