Epidemiology and etiological characteristics of hand,foot and mouth disease in Huizhou City between 2008 and 2011
作者单位:Center for Disease Control and Prevention of Huizhou Huizhou Municipal Central Hospital
会议日期:2014年
学科分类:1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
基 金:National Key Technology R&D Program in the 11th Five-Year Plan of China(2010ZX10004213)
关 键 词:Hand Foot and mouth disease Enterovirus Epidemiologic features Human enterovirus 71 Phylogenetic analysis
摘 要:To study epidemiological features and etiological characteristics of hand,foot and mouth disease(HFMD),42,012 cases were investigated from April 2008 to December 2011 in Huizhou,*** average incidence rate was 21.16 per 10,*** highest peak of HFMD incidence was detected between April and July each year,accounting for 55.93%of all reported cases;another peak occurred in October through December,accounting for 24.17%of the *** the reported cases,89.75%were in children less than 4 years old,and there was a slight predominance of HFMD in boys and children living in rural and suburban *** major pathogens causing HFMD were enterovirus 71(EV71) and coxsackievirus AI6(CA16).C4 a was the most prominent EV71 subgenotype circulating in *** founding provides insight for developing public-health interventions for the control and prevention of HFMD,especially for reducing the risk of HFMD in high-risk individuals by taking precautions against enterovirus infections.