Design,Synthesis and Evaluation of Indolebutylamines as a Novel Class of Selective Dopamine D3 Receptor Ligands
作者单位：复旦大学药学院药物化学教研室 上海药物研究所 苏州大学药学院药理教研室
会议名称：《2012长三角药物化学研讨会》
会议日期：2012年
学科分类：1007[医学-药学(可授医学、理学学位)] 100701[医学-药物化学] 10[医学]
摘 要：D3R has been proved to be a promising therapeutic target for the treatment of schizophrenia, Parkinson’s disease,drug-induced dyskinesia,drug addiction/and drug ***, function study of D3R in vivo is limited due to the lack of highly selective ligand to the receptor, although considerable efforts have been devoted to the design and development of potent and selective ligands for *** date,most D3R selective ligands were 4-Phenylpiperazines and its