CYP46A1 intron-2 T/C polymorphism and Alzheimer's disease:an updated meta-analysis of 16 studies including 3960 cases and 3828 controls
作者单位:Department of NeurologyThe Second Affiliated HospitalSchool of MedicineNanchang University
会议名称:《中华医学会第十七次全国神经病学学术会议》
会议日期:2014年
学科分类:1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
摘 要:Whether the variations in the cholesterol24S-hydroxylase(CYP46A1)gene would raise Alzheimer’s risk is still undetermined,A previous meta-analysis about the association between AD susceptibility and CYP46A1 intron-2 TIC(rs754203)has led to inconsistent *** assess the relationship between the CYP46A1 rs754203polymorphism and AD risk more exactly,relevant