Constructing Protein Structures in the Membrane:Reaping the Benefits from all Protein Structures

作     者：W.Bret Church Hong Wing Lee Hong Ching Lee Lawrence K.Lee Alexander A.Campbell Noeris K.Salam Emma M.Rath Tim Werner 

作者单位：Faculty of PharmacyUniversity of SydneySydney NSW 2006 Australia Victor Chang Cardiac Research InstituteLowy Packer Building405 Liverpool StDarlinghurst NSW 2010 Australia 

会议名称：《2011年全国药物化学学术会议——药物的源头创新》

会议日期：2011年

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

摘      要：正Integral membrane proteins are a class of protein with domains that traverse the membrane, and as a class of molecule important as drug targets have effectively not been available for structure-based drug *** location gives them fundamentally important roles for the cell, and hence the importance as drug targets,yet their environment is the very reason why